When to Choose AOD-9604: AOD-9604 is particularly well-suited for individuals seeking selective fat metabolism enhancement without broader hormonal changes, those who have not responded adequately to diet and exercise alone for stubborn fat reduction, individuals who cannot tolerate or are contraindicated for GLP-1 agonists or growth hormone, athletes needing body composition improvement without affecting glucose regulation or hormone levels, and those preferring a well-researched peptide with established safety data from clinical trials
A ball-and-stick structural diagram of glutathione disulfide, showing two glutathione tripeptides linked by a central disulfide (SS) bond between cysteine residues
These changes can be significantly alleviated by pretreatment with AS-IV (Tu et al., 2013)
Peptide-conjugated biodegradable nanoparticles as a carrier to target paclitaxel to tumor neovasculature
However, the compound is not available through standard pharmaceutical channels in the United States, creating a complex sourcing landscape
PMID: 35563172 mBio 2023 Feb 28;14(1):e0237022