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It links the gastric origin of the molecule (cytoprotection of the mucosa) with its regulatory action at the vascular level

As summarized by Stier, Vos, and Kenley in 2013, the pre-specified primary endpoint for statistically significant weight change across the dose range and study duration was not met, while the compound's tolerability profile remained comparable to placebo

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In addition to GSDMD, other mammalian gasdermin family members, GSDMA, GSDMB, GSDMC, and GSDME, may also undergo palmitoylation at the NT structural domain (79)

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Both of which are entirely appropriate