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Vitamin B12 plays a critical role in the function of the nervous system, and a deficiency can lead to a variety of neurological symptoms, such as numbness, tingling, and difficulty with balance and coordination

Heterophile antibodies rarely affect B12 assays, because most capture the vitamin with intrinsic factor instead of an antibody

While alpha diversity measures did not significantly differ between groups, beta diversity principal coordinates analyses suggested that mice from the same treatment group were the most similar

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Thus the best-known "function" of B 12 (that which is involved with DNA synthesis, cell division, and anemia) is a facultative function that is mediated by B 12 -conservation of an active form of folate which is needed for efficient DNA production