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Neuroimaging data further indicated that carriers of the 168Ser allele displayed enhanced blood oxygen leveldependent activation in the globus pallidus during feedback-related reward processing, suggesting altered reinforcement sensitivity within basal ganglia circuits [73]

Previous studies have demonstrated that IGF- 1 deficiency contributes to vascular rarefaction and impaired vasodilation in the brain [18, 21, 29, 44], yet the consequences of IGF- 1R deficiency in skeletal muscle endothelium remain unclear

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Zhou J, Zhou H, Tang J, Deng S, Yan F, Li W, Qu M (2016) Carbon dots doped with heteroatoms for fluorescent bioimaging: a review