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Deciphering relationship between depression and microbial molecules based on multi-omics: a case study of Chaigui Granules

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In a study conducted by Labib et al., four innovative series of tetrazole analogs were developed by bioisosteric substitution of the sulfonamide moiety in celecoxib (Figure 5) with tetrazole, incorporating various core structures such as chalcone, isoxazole, and pyrazole (96)