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GLP-1 receptor agonists like semaglutide work through a different mechanismthey mimic the glucagon-like peptide-1 hormone to regulate blood sugar, slow gastric emptying, and promote satiety

A GLP1R natural missense variant, A316T, protects against T2D and cardiovascular disease

Oncogenesis (2021) 10:47

Without it, a significant portion of your weight loss comes from lean mass rather than fat, which slows your metabolism and makes future weight regain even more likely

July 10, 2023