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HPLC for purity, mass spectrometry for identity

Key milestones are annotated on the timeline, including the identification of GLP-1 and GLP-2 through gene sequencing in 1983, the extraction of Exendin-4 from Gila monster venom in 1991, and the first FDA approval of a GLP-1 analog, Exenatide, in 2005

Viral vectors for gene therapy: translational and clinical outlook

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Weight loss, particularly rapid weight loss often seen with these drugs, inevitably involves the loss of both fat mass and lean body mass (muscle)