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Some work also links DSIP with body temperature and pain perception

Transcriptomics revealed that CFTR knock down cells are characterized by an upregulation of oxidative stress response-related genes like those expressing for GSH consuming enzymes (i.e., GPX1 , GPX4 ), SOD1 and 2 , peroxiredoxin and thioredoxins

Preclinical data shows that DSIP can modulate the hypothalamic-pituitary-adrenal (HPA) axis, which is our central stress-response system, and it might even influence cortisol and ACTH dynamics

doi: 10.3390/antiox10091442 118

Davies, J