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This regulation covers aflatoxins (AFB1, AFB2, AFG1, AFG2, and AFM1), citrinin (CIT), deoxynivalenol (DON), ergot sclerotia and ergot alkaloids, fumonisins (FB1 and FB2), HT-2 and T-2 toxins, ochratoxin A (OTA), patulin, and zearalenone (ZEN) (European Commission 2023)

In our study, we used different doses of Dihexa, which can be orally administered and cross the BBB in APP/PS1 mice

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Together, these findings strongly highlight aloxistatins dual mode of action and underscore its promising potential as a repurposed therapeutic candidate to treat cardiac fibrosis and the maladaptive progression toward heart failure