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These adverse effects are thought to be rare but should be considered by people who wish to use GLP-1 medications for weight loss
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CJC-1295 is a synthetic analogue of growth hormone-releasing hormone (GHRH), while Ipamorelin is a selective growth hormone secretagogue meaning it stimulates the pituitary to release growth hormone with fewer off-target effects than older compounds
Both compounds likely achieve this by inhibiting Ca + influx by blocking VGCCs (310)
Placental transfer of sitagliptin was observed in pregnant rats and rabbits
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