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Although the exact mechanism linking low serotonin levels to migraine pathology has not yet been fully described (Hamel 2007), researchers have hypothesized that serotonin may interfere with pain processing in the brain

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Protection of the BBB, the inhibition of the elements of the brain microvascular damage such as impairment of tight junctions, increased vesicular transcytosis, production of various cytokines, chemokines and reactive oxygen species offers novel therapeutic targets [11]

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Additional Information How to cite this article : Chen, Y