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Semaglutide itself doesn't directly cause bruising, but the mechanical act of injecting into this delicate tissue creates temporary inflammation and fluid leakage that appears as discoloration

The BiTE (bispecific T-cell engager) platform: Development and future potential of a targeted immuno-oncology therapy across tumor types

This creates positive pressure inside the vial, which forces liquid back through the needle on subsequent draws, increasing contamination risk

Bottom line: While itching can be annoying, it is usually temporary

The demographic, virological, and clinical features of the 139 patients are shown in Table 1

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