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TIME Magazine

Several studies have identified the long-term effects of GLP-1

So when you remove the GLP-1 medication, that patient is set back on a course of weight increase. In other words, without the medication to block and promote pathways that can affect a bodys biochemistry, a person is more likely to return to consuming more calories and regaining weight

Sweet cravings may occur as the body adjusts to improved glycaemic control or due to changes in taste perception and food preferences

Weight loss was the most common outcome, with median satisfaction ratings of 8.5

Beyond its metabolic effects, tirzepatide significantly reduces appetite and food intake through both peripheral and central mechanisms