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Patients are often compound heterozygote with a combination that includes at least one novel mutations or VUS

Elbow pain can result from injuries, overuse, or degenerative conditions in the joint

PMID 22221769

They are commonly used in healthcare settings, including hospitals, clinics, and research laboratories, where maintaining a sterile environment is important

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For instance, the ketone body -Hydroxybutyrate (OHB) has been observed to induce neuronal quiescence and enhance neuronal respiration, and potentially slow down the aging process by delaying the G1 to S phase transition (Koppel et al