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Other promising compounds are French maritime pine bark extract62,63 and marine complexes.70 The Future of Systemic Treatments for Skin Aging Cellular senescence, which is characterized by cell cycle arrest and changes in the epigenome, transcriptome, proteome, and secretome, is attracting increasing attention in the setting of skin aging

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That age-related decline is part of what drew sustained scientific attention to the compound in the first place

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