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ATP is essential as the main energy source for cells, making CoQ10 vital for maintaining cellular energy metabolism (Rimle et al., 2025)

The other approved anti-fibrotic drug, nintedanib, is a non-specific tyrosine kinase inhibitor, which prevents the phosphorylation multiple targets involved in the development of fibrosis including platelet-derived growth factor receptor (PDGFR), fibroblast growth factor receptor (FGFR), vascular endothelial growth factor receptor (VEGFR) as well as the type II TGF- receptor (105, 106)

Takenaka T, Inoue T, Miyazaki T, Hayashi M, Suzuki H

When the desensitized GSH I-encoding gene gshA * was cloned, the activity of the mutant GSH I increased tenfold compared with the wild type enzyme

SAMe also functions as a precursor molecule for glutathione and promotes polyamine synthesis to promote healthy cellular function