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doi: 10.1080/15548627.2025.2481126 53 BhattiJSBhattiGKReddyPH

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This can result from chronic inflammation, poor diet, lack of sleep, overtraining, illness, or environmental toxin exposure

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A recent trial provided creatine to patients suffering from fatigue and found that 6g administered daily was associated with improvements in fatigue and strength . Neuroprotection and Mental Clarity You may not think of creatine as a brain health supplement, but the brain uses approximately 20% of your total resting energy