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Generally, after renal tubular epithelial cell injury, surviving renal tubular epithelial cells undergo dedifferentiation and proliferation to repair the damage [11]

The DAC version provides prolonged stimulation of the GH/IGF-1 axis, while the non-DAC version produces a shorter, more pulsatile signal that more closely resembles the natural physiology of growth hormone release

images were captured with the attached digital camera (Olympus Dp25, Japan)

Nature Immunology , 24 (1), 162173

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