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Similar content being viewed by others Introduction Cholangiopathies are a diverse group of diseases characterized by damage to the cholangiocytes leading to compromised bile secretion and flow which progress to liver fibrosis and, ultimately, cirrhosis

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Consistent with these findings, our present and previous studies confirmed that endothelium-dependent vasodilation is significantly impaired in IGF- 1R KD mice [22, 44]

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