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The incretin-related therapies dipeptidyl peptidase-4 (DPP-4) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) not only improve glycaemic control with a low risk of hypoglycaemia but can also have beneficial non-glycaemic effects such as avoidance of weight gain, reduced blood pressure and improvements in beta-cell function and cardiovascular risk biomarkers 1 3

MassLynx and TargetLynx software (Waters) were applied for the acquisition and analysis of data

Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE

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The dark side of GLP-1 receptor agonists primarily revolves around gastrointestinal issues, such as nausea

Mol Ther Methods Clin Dev 13:334343