The idea is not baseless: dose-response curves for GH secretagogues do plateau, and the Bowers work explored GHRP across a 0.1 to 1.0 mcg/kg range, so a saturation region in that neighborhood is a reasonable-sounding extrapolation
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Human experimental design Eight healthy men (age, 35.9 2.0 y
However, a one-year randomized, double-blind, placebo-controlled trial in 253 elderly (65 years) adults with elevated homocysteine levels found that B vitamin supplementation (1,000 g/day of folate, 10 mg/day of vitamin B 6 , and 500 g/day of vitamin B 12 ) did not improve measures of cognitive function, including memory, despite lowering homocysteine levels (116)
Oxidative stress biomarkers (8-isoprostane) decreased by 35%
During oxidative stress, Keap1 undergoes modifications that inhibit its interaction with Nrf2, allowing Nrf2 to accumulate and activate the expression of antioxidant and cytoprotective genes