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4.2 Enhancing CAR T-Cell safety with peptide-based approach A recent Phase 1 first-in-human trial exploring PSCA-CAR T cell therapy has shown promising bioactivity and initial signs of clinical success

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These potential pathways are summarized in Figure 5 and warrant further translational research for validation

Mice had free access to food and water and were housed in a room with a 12 h light/12 h dark cycle (07:0019:00 h), ambient temperature at 1923 C and humidity at 4070%

By blunting dopamine release and reducing reward signaling in these areas, tirzepatide could theoretically reduce cravings for various substances and even non-substance compulsive behaviors