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Specifically, the peptide upregulated Bcl-2 expression while suppressing Bax, two central regulators of the intrinsic apoptotic pathway

Death ligand TRAIL, secreted by CD1a + and CD14 + cells in blister fluids, is involved in killing keratinocytes in toxic epidermal necrolysis

Soluble and crystalline UA can have opposing effects on innate immunity, and only microcrystal-free UA preparations provide reliable results [50]

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Seizure activity may spread to adjacent structures of the limbic-hypothalamic-pituitary axis in the brain, which might be responsible for the varied symptoms that occur among patients with ME/CFS