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10.1152/ajpendo.1989.257.6.E916 Am

Twelve people were enrolled for eight weeks, and dose response established the highest dose at 720 mg

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For individuals receiving B12 injections for severe deficiency, there have been isolated reports of hypokalaemia (low potassium) during initial treatment, as rapid cell production consumes potassium

Patch testing before full application is always a good idea