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Variants in genes like GLP1R (rs6923761) and MC4R (rs17782313) influence how strongly you respond to GLP-1 therapy and how sensitive your digestive system may be to triggers like alcohol
Safety and Tolerability Overall, GLP-1 RAs are well tolerated, with GI symptoms being the most common adverse events (AEs), such as nausea, vomiting, diarrhoea, constipation and abdominal pain
Mackenzie PI, et al
Exceptional tumour responses to fasting-mimicking diet combined with standard anticancer therapies: a sub-analysis of the NCT03340935 trial
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Thats why B12 injections are often given as treatment
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![GLP-1 Agonists Can Be Heaven or Hell Dependent Upon Dopaminergic Genetic/Epigenetic Antecedents[v1]](https://www.preprints.org/frontend/picture/ms_xml/manuscript/c9c3cd16d3db64faa79714c50b5bb790/preprints-181961-g001.png)
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