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The prophylactic regimen was 40 to 60 IU/kg of ADYNOVATE twice a week, with a mean (SD) dose of 51.1 IU/kg (5.5)

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Effect of human insulin-like growth factor-binding protein-1 on the half-life and action of administered insulin-like growth factor-I in rats

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Agents that inhibit somatostatin secretion or action might reduce the risk of insulin-induced hypoglycaemia and should be considered as an adjunct to insulin therapy