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However, in people with reduced kidney mass, hyperfiltration can occur despite the whole-kidney GFR being in the normal range, a condition referred to as single-nephron hyperfiltration

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This highlights the need for concurrent strategies such as exercise, adjust dietary intakes, other long-term lifestyle support and need for nutritional screening to reduce the risks of long-term adverse outcomes (4)

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Liraglutide, the active comparator, was initiated at 0.6 mg daily and titrated weekly up to 3.0 mg

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