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Nasal delivery avoids injection site risks (infection, bruising, irritation) but introduces nasal mucosal irritation and formulation stability concerns

Status: Research phase No completed human RCTs Not FDA-approved SC injection or oral (research only) Caveat: BPC-157 is under review at the FDA's July 2026 peptide advisory panel and is currently restricted for compounding

Wang, G

Open Neurol

While short-term anti-inflammatory effects can be helpful, long-term immune regulation --- especially in patients with autoimmune conditions --- needs careful monitoring

Risks and Side Effects While B12 shots are generally very safe, you should be aware of a few risks: Injection Site Pain: You might feel mild soreness or see redness where the shot was given