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In totality, alcohol leads to central effects on LV diastolic hemodynamics, vascular endothelial dysfunction and activation, and a proinflammatory milieu

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Many individuals find that eating 4 to 5 small meals daily dramatically improves tolerability at higher doses

Practices that measurably reduce cortisol: regular exercise (moderate intensity, not exhausting), adequate sleep (7-9 hours), mindfulness or meditation practice, limiting catastrophic thinking about hair loss, and maintaining social connections