Appetite suppression often becomes stronger as the dose is gradually increased
However, gastrointestinal side effects such as constipation may indirectly contribute to conditions like haemorrhoids or anal fissures that cause rectal bleeding
The common gastrointestinal side effects are manageable and tend to improve over time
Patients with Type 2 diabetes have many other drug treatment options, including other GLP-1 receptor agonists like Mounjaro (tirzepatide) and Trulicity (dulaglitude)
The tension between semaglutides and body acceptance is palpable
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