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In fact, HIEC proliferation and TEER significantly increases when co-cultured simultaneously with both cell types, advocating for the importance of developing complex OoC systems that can generate more biologically relevant outputs

11 12 GLP-1s lower blood sugar, blood pressure, body weight, and inflammationall of which reduce strain on the heart and blood vessels 13 GLP-1 receptors are found in the heart and arteries, where they may also improve endothelial function, increase nitric oxide, and reduce oxidative stress, helping stabilize plaque and improve how the heart uses energy, especially during stress

Pinchas, S., Silver, B

However, clinicians should remain informed as the field evolves

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