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"Suboptimal sleep impacts endocrine (hormone) secretion and increases cortisol (stress hormone) release in the evening, and these can lead to decreases in concentrations of both growth hormone and IGF-1," Dr

10.1039/d3sc00752a 56 ProchzkovD.BouovI.WilhelmovN

These results provide evidence that the reduction of peripheral GSH pools increases peripheral NGF circulation that orchestrates a neuroprotective response in the CNS, at least in the striatum, through the NGF/TrkA/Akt/Nrf2 pathway

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The broader discussion of peptides for chronic pain conditions may also be relevant for individuals managing complex pain presentations during fracture recovery

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