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Immunity 56 , 16131630.e5 (2023)

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Over the following weeks, patients often report smoother movement, improved tissue quality, and faster recovery from disc irritation, joint inflammation, or tendon strain

Trials conducted between 2001 and 2007 demonstrated statistically significant reductions in body fat, although the larger Phase IIb OPTIONS trial did not replicate these findings at sufficient magnitude for regulatory approval, and formal development was discontinued in 2007

Induction of IDO-1 by immunostimulatory DNA limits severity of experimental colitis