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According to the study on rodents, the time GR took to reach the highest concentration (C max ) for oral administration was 10 min and 5 min for intravenous administration

Furthermore, N-acetyl cysteine (NAC) is clinically used as an antidote to treat paracetamol overdose by replenishing GSH and preventing NAPQI accumulation (Kobrinsky et al ., 1996)