The net effect would depend on which compartment is most affected in a given individual
Extra caution is advised in people with: A history of pancreatitis Severe acidity or gastroparesis (very slow stomach emptying) Known gallstones or gallbladder disease Advanced kidney disease Significant diabetic eye disease (retinopathy) A very low BMI or a history of eating disorders Pregnancy, plans to become pregnant, or breastfeeding, since some GLP-1 medicines stay in the body for several weeks after stopping Significant depression, who should be monitored carefully Upcoming surgery, endoscopy, or a procedure needing anaesthesia or sedation, since delayed stomach emptying can raise aspiration risk and temporary stopping may be advised How GLP-1 side effects usually progress: a typical timeline Every person is different, but clinical practice and studies suggest a rough pattern [6]: First 2 to 6 weeks: nausea, early fullness, and constipation are most common
[DOI] [PubMed] [Google Scholar] 868.Mansur S.A., Mieczkowska A., Flatt P.R., Chappard D., Irwin N., Mabilleau G
Venkatasubramani N, Venkatesan T, Li BU
it changes the delivery
How to Use GLP-1s the Right Way for Long-Term Results If youre currently using a GLP-1 medicationor considering itthe most important question you can ask yourself is this: Am I using this tool to build habits that will last