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The CNSs high metabolic demand renders it particularly vulnerable to oxidative injury

These may cause little or no pain for years

Zhang J, Wang X, Vikash V, Ye Q, Wu D, Liu Y, et al

Weight reduction and reduced adiposity probably contributed significantly, but additional mechanisms may also be involved, such as improved insulin sensitivity, reduced inflammation, reduced aromatization for the adipose tissue, and potentially a restoration or improvement of the hypothalamic-pituitary-gonadal axis," he noted

Gandolfo LC, Bahlo M, Speed TP

These drugs help control blood sugar levels by increasing insulin production and reducing the amount of sugar the liver releases