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Taken together, metal-based cargos of CRISPR-Cas can open novel ventures for delivering gene-editing tools that can serve as potential therapeutic technology to be used in actual clinical settings [183-187] (Fig

Furthermore, uncertainty in accounting for individual patient variability, such as genetic predispositions, disease stage, or coexisting conditions, makes available drugs less effective across diverse patient populations 78

Although Ozempic is FDA-approved to treat type 2 diabetes and not weight loss, some physicians prescribe the drug off-label to help patients manage their weight

Colhoun, R

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