Behavioral weight loss interventions to prevent obesity-related morbidity and mortality in adults: US Preventive Services Task Force recommendation statement
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Cho S, Lee YH, Park H et al (2001) Glutathione S-transferase mu modulates the stress-activated signals by suppressing apoptosis signal-regulating kinase 1
doi:10.1210/jcem.86.8.7747
These structural differences may affect how they interact with GLP-1 receptors in the gastrointestinal tract and central nervous system, which could contribute to differences in nausea experienced
For example, in a patient with intentional overdose who is also on a GLP-1 agonist, the time to peak concentration of co-ingested agents may be prolonged, complicating risk assessment, decontamination decisions, and timing of antidotal therapies