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The results were heterogeneous: some trials, such as AMPLITUDE-O and SELECT, demonstrated significant reductions in HF-related endpoints, whereas others, like LEADER, showed only non-significant favourable trends

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The market is growing due to the rising prevalence of diabetes and obesity, driving demand for effective treatment options

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Evidence signal Source-backed review Regulatory reality Access rules depend on the compound and patient situation Safety screen Viral claims can miss contraindications, dose escalation, medication interactions, and quality-control risks