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In REDEFINE 1 (NEJM 2025, n=3,417, 68 weeks), cagrilintide monotherapy at 2.4 mg produced 11.8% mean body-weight reduction versus 2.3% with placebo

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Int J Mol Sci 22(2):715

Interestingly, mRNA and protein expression levels of CYP24A1 that degrade 25(OH)VD are upregulated in the liver of mice fed HFD in comparison with mice fed normal diet

B., Rivera, L

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