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186 Additionally, A-485, a CoA-competitive p300 inhibitor, decreases YY1 lactylation in human microglial clone 3 cells, ultimately hindering retinal neovascularization

High-fat diet-induced colonocyte dysfunction escalates microbiota-derived trimethylamine n-oxide

Collectively, these early explorations revealed the potential but also the limitations of simply repurposing existing drugs, emphasizing the need for therapies tailored to the unique biology of ICH (Fig