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Whether you're taking semaglutide or tirzepatide, the day-to-day nutrition priorities are similar: enough protein, steady fluids, fiber you tolerate, and meals that still work when appetite is low

However, current clinical trials have not shown a significant difference in side effect rates between GIPR/GLP-1R dual agonist and GLP-1RA alone

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While these percentages are close to rates of side effects like nausea, diarrhea and constipation experienced by younger adults, experts point out that the consequences can be more serious for seniors

Furthermore, there is a well-documented vicious cycle between estrogen and histamine, which is why MCAS often flares in women during hormonal shifts