Scientists at The Scripps Research Institute (TSRI) have developed a vaccine that blocks the pain-numbing effects of the opioid drugs oxycodone (oxy) and hydrocodone (hydro) in animal models
"Triple-Hormone-Receptor Agonist Retatrutide for Obesity A Phase 2 Trial." New England Journal of Medicine 2023;389:514526 Wilding JPH, et al
Contradictory Evidence: Possible Antidepressant Effects of GLP-1 GLP-1 receptor agonists have been studied for their mental health side effects
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Since sleep apnea is caused largely by excess weight compressing the airway, reducing that weight relieves the mechanical cause
Animal studies by Carla Nasca, a postdoctoral scholar in McEwens lab, suggest that acetyl-L-carnitine, a crucial mediator of fat metabolism and energy production throughout the body, plays a special role in the brain, where it works at least in part by preventing the excessive firing of excitatory nerve cells in brain regions called the hippocampus and frontal cortex
