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In neurodegenerative disorders and ischemic brain injury, ferroptosis inhibition may be beneficial because neurons are highly vulnerable to oxidative stress and lipid peroxidation

Because it is so central to human biology, having optimal levels is often associated with feeling more vibrant and focused

GHK was also shown to combat copper-dependent oxidation of low-density lipoproteins, while various other common antioxidants, such as superoxide dismutase, only provided protection against oxidation up to 20%

That tells you that theres probably brain inflammation

Therefore, to validate our results in a suitable rodent model of HD, we used striatal tissues from 8-month-old SPRDtgHD and respective controls

In neuronal tissue, SERT reversal leads to a transient elevation of synaptic 5HT and potentiation of 5HT signaling