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While KA activates Notch signaling, activity of CyclinD1 is increased through AKT/glycogen synthase kinase-3 (GSK-3) signaling pathway, which leads to the transformation and abnormalities in G 1 -S in CCR [64]

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This is a process where free radicals "steal" electrons from the lipids (fats) in cell membranes, causing cell damage

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