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Most studies have been short-term, and the long-term effects of semaglutide on PCOS remain unknown

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In preclinical and in vitro models, the mechanism of retatrutide involves potential simultaneous engagement of three G protein-coupled receptors

428 PDK4 deficiency enhances hepatic glycolysis by increasing the GCK level and improving insulin sensitivity during liver regeneration

Additionally, the medication's effect on gut motility may alter the normal passage of gas through the digestive tract, with colonic fermentation contributing to flatulence

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