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HTA assessment, including pricing and reimbursement activity across the globe, will increasingly account for patient experience data alongside conventional economic analyses

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Sirtuin activation: SIRT1 through SIRT7 are NAD+-dependent proteins that regulate gene expression, inflammation, and cellular stress responses

Through network pharmacology and molecular docking, key proteins like SIRT1, ESR1, and NGF show strong interactions with capsaicin, suggesting a promising neuroprotective effect