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La niacina, en forma de NAD+ y NADP+, es requerida como cofactor en pasos previos de la sntesis de carnitina y tambin es esencial para el funcionamiento de deshidrogenasas involucradas en la beta-oxidacin de cidos grasos, proceso central que depende del transporte de cidos grasos mediado por L-Carnitina

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This allows MCFAs to be effectively converted into energy for its immediate utilization rather than being involved in cholesterol biosynthesis and fat accumulation (Duttaroy 2021)

Additionally, BER prevents the activation of the LRR, NACHT, and PYD domain-containing protein 3 (NLRP3) inflammasome during PD-related inflammation and restores autophagy activity that safeguards dopamine neurons [24]