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The strength of evidence depends on the specific application you're considering

This release of histamine and tryptase increases blood flow to the skeletal muscles during exercise.[ref] Hypoxia has also been shown to induce mast cell degranulation.[ref] This is a normal response for most people, and the body can handle a certain increase in histamine and tryptase

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The mixed signals regarding the peptides interaction with malignant cells lead regulatory scientists to unequivocally conclude that BPC-157 poses an unacceptable risk to individuals with active or suspected malignancies, as introducing a potent growth-promoting angiogenesis catalyst into an oncological environment could be catastrophic

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