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During pathological conditions, cytokines can also stimulate inducible nitrogen oxide synthase (iNOS) which results in the production of NO in astrocytes and microglial cells (Murphy, 2000), which can then combine with superoxide radicals to form the aforementioned peroxynitrite, facilitating excitotoxicity (Leist et al., 1997) and DNA damage, ultimately leading to cell death (Xia et al., 1996)

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I recommend a holistic approach to health As always, a holistic health strategy is paramount, and collagen supplements should be part of a balanced lifestyle inclusive of a nutritious diet and regular exercise